Enzyme-responsive supramolecular nanovalves crafted by mesoporous silica nanoparticles and choline-sulfonatocalix[4]arene [2]pseudorotaxanes for controlled cargo release.
نویسندگان
چکیده
Mesoporous silica nanoparticles (MSNs) have been surface-functionalized with choline moieties encircled by sulfonatocalix[4]arenes. Two enzyme cleavable sites are incorporated in the stalks for specific enzymes to regulate the release of loaded cargos from MSNs. These gated materials show a clear enzymatic response and proven orthogonality.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 79 شماره
صفحات -
تاریخ انتشار 2013